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Today, celery seed is used mostly as a diuretic, meaning it helps your body eliminate water by increasing urine output. Pregnant and nursing women should avoid eating celery seeds as they may cause uterine bleeding and premature contractions (x). 2008;63(2):243-4. Celery is POSSIBLY SAFE for most people when taken by mouth or applied to J Vector Ecol. DOI: sciencedirect.com/topics/agricultural-and-biological-sciences/apium-graveolens, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT. Contains 75 mg celery seed/63.75 mg 3nB extract per.Celery is often called a negative calorie food but it certainly isnt lacking in nutrition. View abstract. It can lead to severe pain, redness and swelling. Johansson, S. G., Dannaeus, A., and Lilja, G. The relevance of anti-food antibodies for the diagnosis of food allergy. Crispy, crunchy celery has a number of benefits that may surprise you. Celery seed extract Health benefits, dosage, safety, side-effects Zheng GQ, Kenney PM, Zhang J, Lam LK. Ko FN, Huang TF, Teng CM. Antioxidant, anti-inflammatory, antimicrobial, GI, and cytotoxic effects of celery have been described. 1986;4(3):195-199. The most notable compounds in celery seed include: These compounds have been researched for their role in inflammation and uric acid production, which is a driving force behind the severity of gout attacks. Celery seeds contain NBP, an oily compound with a diuretic effect that helps with the detoxification process. 2005;221(1):11-20. Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. Am J Health Syst Pharm 2000;57:1221-7. Oral hyposensitization with celery juice. View abstract. Australian Prescriber 2001;24:6-7. What is the Proper Dosage?Lets take a closer look at the benefits, dosages, and side effects of using celery seed for gout. Occasional consumption as part of a well-balanced diet is not an issue. When blood pressure is reduced, the chances of developing atherosclerosis, heart attack or stroke also drops. Inhibitory effects of, Kooti W, et al. and tightening of the airways, Shock, along with a severe drop Celery is a popular vegetable, but theres more to this plant than the stalk alone. OTHER NAME(S): Aches des Marais, Ajamoda, Ajmoda, Ajwan, Apii Fru. Therefore, researchers suggest that extract from the seeds may have potential as a natural food preservative (27). 1992;10(6):613. Theyre small, light-brown, and have an earthy scent. 2004;98(4):407-17. Since then, the plant has been widely used as a food and for medicinal purposes. Am.J.Emerg.Med. In fact, one large review associated magnesium-rich diets with an up to 14% reduced risk of diabetes (21, 24). A small study in elderly patients with hyperglycemia (N=16) evaluated the effect of celery leaf on blood glucose and plasma insulin levels. (2017). J Ethnopharmacol. Celery continues to be used as a food flavoring and in soaps and gum. Through dietary interventions, you may be able to reduce the levels of uric acid in the blood and minimize painful flare-ups. A tablespoon of celery seed contains 17 percent of the recommended daily value of iron, which is a significant boost for at-risk groups or those looking to increase their hemoglobin levels. Wuthrich, B., Borga, A., and Yman, L. Oral allergy syndrome to a jackfruit (Artocarpus integrifolia). Current research on celery seed has shown benefits at the following dosages: Research studies on celery seed, like many botanical medicine studies, primarily use hydroalcoholic extracts. Bleeding may occur. However, various research studies may give us a starting place for beneficial dosages in humans. Silverstein, S. R., Frommer, D. A., Dobozin, B., and Rosen, P. Celery-dependent exercise-induced anaphylaxis. Gout is a chronic inflammatory condition marked by the buildup and crystallization of uric acid in the joints and tissues. ARYA Atheroscler 2016;12(5):248-9. View abstract. Miller L. Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions. Celery: Health Benefits, Nutrients, Preparation, and More Moreover, these compounds fight against certain cancers including intestinal cancer, breast cancer and leukemia by preventing mutated malignant cells from multiplying (x). View abstract. It is best to take celery seed extract in 1,000 mg increments once to three times daily, or as recommended by a doctor. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. During ancient times, Indian Ayurvedic medicine used celery seed to treat colds, flu, water retention, poor digestion, different types of arthritis, and certain diseases of the liver and spleen. It seems that my body is just really resistant to these supplements. View abstract. Fresh celery contains important nutrients but celery seed extract in supplements may cause side effects. Celery seeds are a versatile spice. Anti-gouty arthritis and anti-hyperuricemia properties of celery seed extracts in rodent models. View abstract. Combined with anise and saffron, celery seed extract is used to treat menstrual discomfort and reduce fluid retention(x). Asia Pac J Pharmacol. Hessami K, Rahnavard T, Hosseinkhani A, et al. Your lithium dose might need to be changed. Apiole has been used for centuries as an abortifacient: an herb used to cause a deliberate miscarriage. Celery contains chemo-protective compounds known as polyacetylenes, which have immune-boosting benefits. (Paris) 1995;27(6):209. View abstract. Palgan K, Gtz-Zbikowska M, Tykwinska M, Napirkowska K, Bartuzi Z. Celery-cause of severe anaphylactic shock. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. This information may not fit your specific health circumstances. 2012;66:132-4. Celery seed contains compounds that may be beneficial in the treatment of gout. This type of iron is different from heme iron in animal products and is absorbed at a lower rate at roughly 10% (15). WebOral administration of celery seed extract (300 mg/kg) for six weeks prevented an increase in oxidative stress and hepatic enzyme and bilirubin levels. In addition, potential celery seed benefits include the treatment of ailments such as edema, gout, flatulence, chronic pneumonia and obesity. Celery seeds consist of the oil (petroselinic, linoleic, palmitic, and oleic fatty acids) and volatile compounds, mostly monoterpene hydrocarbons.Kooti 2017 The major Moneret-Vautrin, D. A. and Kanny, G. [Food-induced anaphylaxis. If you notice negative side effects when taking herbal supplements, see your doctor. This information relates to an herbal, vitamin, mineral or other dietary supplement. J AOAC Int 2001;84(4):1135-1143. DeChamp, C., Michel, J., Deviller, P., and Perrin, L. F. [Anaphylactic shock to celery and sensitization to ragweed and mugwort. 2002;27(3):153-156. Eating foods rich in vitamin C like berries, citrus fruits, or bell peppers in meals with the seeds can help optimize non-heme iron absorption (15, 18). If you use celery seed extract, make sure to use sunscreen or sunblock lotions to protect your skin from sunburn. Use them as a spice rub for grilled meat. Some of these include lithium, diuretics, anticoagulants and thyroid medications, according to Penn State Hershey. 2009 Aug;61(8):1067-77. Biochim Biophys Acta. Manganese is needed to activate enzymes that produce proteins necessary for the formation of bone tissue and cartilage. J Emerg.Med 1999;17(2):235-237. Here are five reasons you should consider adding celery to your diet. Vitamin C enhances the absorption of non-heme iron in plant foods like celery seeds. 3-n-butylphthalide (3nB) is another compound from celery that may have benefits against gout inflammation. Celery Seed Oleoresin is a natural extract derived from the seeds of the celery plant. DOI: Vieira AT, et al. Here are a few recommendations for celery seed supplements that might be beneficial for gout, although you should speak with your doctor first: Natural Factors View abstract. Taking celery juice with aminopyrine might increase the effects and side effects of aminopyrine. 2000;57(13):1221-1227. Blood-thinning medications (anticoagulants and antiplatelets): Celery seed contains chemicals that may thin the blood. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Including magnesium-rich foods like celery seeds in your diet may reduce your risk of type 2 diabetes. Symptoms of celery allergy can afflict your mouth, with itching and swelling of the lips, tongue and throat, reports the University of Nebraska - Lincoln. We avoid using tertiary references. If you experience any of the following symptoms, get immediate medical attention: Before taking a supplement containing celery seed extract, ask your doctor if you are on any medication that may interact with the herb. Though research is limited, a few animal and test-tube studies have found celery seed extract to possess antioxidant properties (1, 29). 1996;135(2):334. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. One of the most well-known minerals for bone health is calcium. The presence of potentially toxic polyacetylenes, including falcarinol and falcarindiol, in celery has been described. Hepatoprotective activity of Apium graveolens and Hygrophila auriculata against paracetamol and thioacetamide intoxication in rats. This could change the effects and side effects of these medications. Allergy 1997;52(4):428-431. Additionally, celery seed supplements may interact with certain medications. In about 450 BC, the Greeks used celery to make a type of wine called selinites, which was given as an award at early athletic games, much like laurel leaves or olive branches. If you have gout, try turmeric as a home remedy. Food Chem.Toxicol. Baek CH, Bae YJ, Cho YS, Moon HB, Kim TB. Theyre particularly rich in various minerals, such as calcium, iron, and manganese. Celery seed has been used as medicine for thousands of years in the Eastern world. Case report. In fact, each pill has a higher dosage of celery seed extract plus the addition of the tart cherry, and at a lower price. This could increase how much lithium is in the body and result in serious side effects. Parts of the celery plant, botanically known as Apium graveolens, have been used therapeutically for thousands of years. Available for Android and iOS devices. Sohrabi F, Niazmand S, Mahmoudabady M, Niazmand MJ. As a result, you may develop iron-deficiency anemia (15). This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. Ballmer-Weber, B. K., Hoffmann, A., Wuthrich, B., Luttkopf, D., Pompei, C., Wangorsch, A., Kastner, M., and Vieths, S. Influence of food processing on the allergenicity of celery: DBPCFC with celery spice and cooked celery in patients with celery allergy. Your bones require certain vitamins and minerals in varying amounts to stay healthy and strong. Celery seed Information | Mount Sinai - New York For this reason, it is important to consult with your healthcare provider before taking supplemental celery seed. This helps your blood vessels to expand and facilitates the smooth circulation of blood and, thus, reduces blood pressure. Incorporate them into your barbeque dishes like coleslaw or potato salad. Influence of certain essential oils on carcinogen-metabolizing enzymes and acid-soluble sulfhydryls in mouse liver. View abstract. Most celery seed studies are either animal studies or in vitro studies, so theres a lack of research exploring celery seed in human dosages. Celery root might slow blood clotting. 3 Cancer Preventive Activity Singh A, Handa SS. If you have a history of heart disease, you may want to start with a lower dose of the herb. The seeds guard against inflammation, which causes health issues like arthritis, cancer and heart disease. Hirschfeld G, Weber L, Renkl A, Scharffetter-Kochanek K, Weiss JM. Celery Seed Extract: Benefits, Side Effects & Dosage J Med Food. WebOne can use the recommended Oriental dosages to lower mild cases of high blood pressure by eating about four ounces of celery per day. Research suggests that certain compounds in celery seed may have benefits in treating gout. Almost 70% of older adults use them. Natural Extracts Lower Blood Pressure - Life Extension Vu N, Nguyen TTT, Parmenter BH, Thouas GA. Safety, efficacy and tolerability of a combination micronutrient and polyherbal preparation (GoutFighter TM) for gout: a single-arm open-label pilot study. In Asian medicine, celery seed is used to treat headaches and as a diuretic, digestive aid, and emmenagogue. Cutis 1993;51(1):41-42. The researchers found that luteolin from celery seeds reduced the production of nitric oxide from uric acid. From lowering blood pressure to fighting inflammation and treating infections, celery seeds offer a multitude of health benefits. Fitoterapia. Am Fam.Physician 1989;39(4):143-146. Heres the science behind the popular trend. Bleeding may occur. Celery originated in the Mediterranean and now grows throughout Europe, Asia Minor and the Himalayas (x). Postepy Hig Med Dosw (Online). For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Here are 6 super seeds to eat for better health. Celery seeds are rich in many essential nutrients for bone health like calcium, manganese, magnesium, and phosphorus. Celery supplements are available as celery seed extract, fresh or dried seeds, tablets and as capsules filled with celery seed oil. Although celery seed and extract is used to treat a number of health conditions, few human studies support this, and you may experience side effects with its use. Magnesium plays an important role in blood sugar control and helps increase your cells response to insulin, a hormone that regulates blood sugar levels (21, 22, 23). IgE cross-reactivity between birch pollen, mugwort pollen, and celery is due to three distinct cross-reacting allergens: immunoblot investigation of the birch-mugwort-celery syndrome. Web1) celery seed extract (tried this after using celery seed on its own to no success) 2) sunflower lecithin. Am J Clin Nutr. A celery seedflavored soda, Dr. Brown's Cel-Ray, is available. (2018). Hypolipidemic and antioxidant activity of mountian celery seed essential oils. 1993;19:77-86. celery seed extract in 1,000 mg increments once to three times daily, or as Vasodilatory action mechanisms of apigenin isolated from Apium graveolens in rat thoracic aorta. WebDose: to 5/8 tsp whole celery seeds, chewed/ground, with breakfast Effect on Cum Volume: Solid increase (~11%) Effect on Sperm Volume: Significant increase (~26%) Effect on Libido: Solid increase, on average, but this effect proved uneven; erections come easier and View abstract. Researchers have found that people who eat a diet rich in lutein, found in celery, spinach, broccoli, lettuce, tomatoes, oranges, carrots, and greens, were less likely to develop colorectal cancer. The coumarin glucoside apiumoside has also been identified. (2010). These extracts have been standardized to contain certain percentages of beneficial compounds, such as luteolin or 3nB. 1990;126(10):1334-1336. View abstract. Healthline only shows you brands and products that we stand behind. A Root Vegetable With Surprising Benefits, 10 Delicious Herbs and Spices With Powerful Health Benefits, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Parmesan Cheese: Nutrition, Benefits, and Uses. There is a cross reactivity with all forms of celery, including celery salt, celery root, celery seed and commercial products that contain celery seed, such as Old Bay seasoning. Celery oil and celery seeds are LIKELY SAFE when taken by mouth in food amounts. Some of the phenolic compounds in celery seeds can cause your skin to become very sensitive to the sun's UV rays, according to Penn State Hershey. J Ethnopharmacol 2021;264:113400. Discover essential oils that can aid in reducing gout symptoms. If you have low blood pressure, you should use caution when considering celery seed extract as a supplement. View abstract. Ground celery seed is often referred to as celery powder. Coronary heart disease is the leading cause of death in many countries. Celery And Its Side Effects | Lybrate CELERY: Overview, Uses, Side Effects, Precautions, You can easily add celery seeds to your diet by adding them to soups, side dishes, and even hot tea. Celery seed oil is a supplement containing a high amount of volatile compounds known as phthalides. DOI: Pauff JM, et al. Consider therapy modification.Choi 2017, Fan 2017, Heck 2000, Izzat 1998, Jiang 2005, Kruth 2004, Lambert 2001, Mousa 2010, Shi 2012, Spolarilch 2007, Stanger 2012, Tsai 2013, Ulbricht 2008, Vaes 2000, Wang 2015, Herbs (anticoagulant/antiplatelet properties): Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of other herbs (anticoagulant/antiplatelet properties). The celery plant is slender and stands about 2 to 3 feet tall. Inhibition of cell adhesion, antiangiogenic properties, proapoptosis, and other effects have been demonstrated in studies using human cancer cell lines.Iyer 2019, Kasiri 2018, Kowalczyk 2017, Sung 2016 In vitro and rodent studies suggest essential oil from celery may also possess cytotoxic and antimutagenic properties.Christensen 2006, Hashim 1994, Lim 2013, Zheng 1993, Celery extract has demonstrated vasorelaxant effects on isolated rat aortic rings.Jorge 2013 Celery seed extract exerted hypotensive effects in hypertensive, but not normotensive, rats, possibly due to the n-butylphthalide content.Moghadam 2013, Tang 2017 Limited studies in rodents report improved lipid profiles with celery seed extracts.Abd El-Mageed 2011, Iyer 2011, Iyer 2019, Rouhi-Boroujeni 2015 Additional effects in cardiovascular disease include decreased secretion of proinflammatory cytokines.Tang 2017, Limited clinical studies have been conducted to evaluate the effects of the extracted compound butylphthalide in strokeWang 2018; one study demonstrated superiority of 90-day treatment with dl-3-n-butylphthalide (a synthetic variation of l-3-n-butylphthalide, an extract from seeds of A. graveolens) over aspirin in patients with acute ischemic stroke.Cui 2013 The synthetic version of the compound is clinically approved as an anti-ischemic agent in China.Abdoulaye 2016, In older studies, 3-n-butylphthalide showed sedative and anticonvulsant effects in rodents.Khan 2009 In induced Parkinson disease models in mice, extracts from whole A. graveolens plant improved behavioral performance, oxidative stress parameters, and monoamine oxidase A and B activity.Chonpathompikunlert 2018, Huang 2010 Other studies in rodents report improvements in cognition and depression, and modulation of endogenous antioxidant and neurotransmitter systems.Boonruamkae 2017 Reviews exist regarding neuroprotective effects of the flavone luteolin, which is found in several plant products, including celery.Nabavi 2015, Clinical studies are lacking. Indeed, celery seed is a natural alternative to synthetic repellents for protection against mosquitoes. Celery seeds trigger the natural production of urine and are beneficial at combating bacterial infections within the digestive tract. Springhouse, PA: Springhouse Corp., 1999. A role for celery in cardiovascular disease, CNS disorders, gout, and diabetes has also been suggested; however, clinical studies are lacking to support a place in therapy.