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While supplements are derived from the black elder (Sambucus nigra) tree, the actual . However, the researchers noted that further research is still needed. View abstract. Supplements (the high quality ones that really work) will act in your body exactly like a drug and the timing impacts efficacy. Have a conversation with your doctor about the risks associated with taking these two supplements together, to ensure the benefits outweigh the risks. However, these claims have limited evidence, and further research is needed. In 2021, the USP held a forum to discuss the need for standards in developing elderberry products. Title 21. Dosage of drugs is not considered in the study. Read more: Confused About Multivitamins? There are three ways you can take elderberry for immune support. Vitamin Keven in foods such as kale, lettuce, broccoli, and chickpeascan counteract a blood thinners benefits. This is a toxin also found in apricot seeds and almonds (1, 34). In addition, a diet high in flavonoids like anthocyanins has been found to reduce the risk of heart disease (17, 22). Learn more about fenugreek's benefits, safety, and side effects here. The bark, unripe berries, and seeds contain small amounts of substances known as lectins, which can cause stomach problems if too much is eaten (2). Read more: Vitamin K: Why You Need It and Where to Find It. Taking antibioticsespecially those in the tetracycline familyalong with iron supplements can dampen the effects of the antibiotics, making them less likely to work, Dr. Glatter says. View abstract. Avula B, Katragunta K, Wang YH, et al. Our website services, content, and products are for informational purposes only. Can You Take Supplements and Multivitamins With Biotin? Unripe or unprocessed berries, as well as other parts of the plant, should not be consumed as they can be poisonous. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182. Elderberry fruits, leaves, and flowers are strong antioxidants. This article will review the potential uses of elderberry, how to safely use it, and possible concerns with using elderberry. Vitamin, supplement, and medication interactions. Diarrhea and constipation. Eur Cytokine Netw 2001;12:290-6.. View abstract. Deficiencies in either can cause extreme exhaustion. Elderberries may have anti-inflammatory, antioxidant, and. View abstract. Never eat or drink any product made from raw elderberry fruit, flowers, or leaves. Follow these tips to stay safe with supplements. Vitamin K, for example, can make blood thinners less effective. This is just 3% of the estimated fatal dose for a 130-pound (60-kg) person (2, 35). Believe it or not, vitamin K is one of the nutrients even nutritionists don't get enough of. The berries are quite tart and need to be cooked to be eaten. In some clinical trials, adults took 3 teaspoons (1 tablespoon) of elderberry extract in syrup form four times daily for five days. These should ideally be taken at breakfast. Whats more, elderberry can increase insulin secretion and improve blood sugar levels. Vitamin C helps your body absorb plant-based iron. The flowers, fruits, and leaves of the elderberry plant are excellent sources of antioxidants. Just because something is natural doesnt mean it is risk-free. Garlic isnt the only supplement that can up your bleeding risk. Additionally, she says to refrain from taking calcium, magnesium or zinc together as they will compete for absorption., While Dr. Jaydeep Tripathy says taking calcium and magnesium helps prevent osteoporosis, in order to maximize the benefits, take them two hours apart. While elderberry has been associated with many promising health benefits, most of the research has only been conducted in a lab setting and not tested extensively in humans. Roschek B, Fink RC, McMichael MD, et al. Jennifer Lefton, MS, RD/N-AP, CNSC, FAND is a Registered Dietitian/Nutritionist and writer with over 20 years of experience in clinical nutrition. One cup (145 grams) of fresh berries contain 106 calories, 26.7 grams of carbs, and less than 1 gram each of fat and protein (3). There is no data evaluating elderberry safety in people who are pregnant or breastfeeding. Sinus infections. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, 4 Natural Supplements That Are as Powerful as Drugs, Berberine A Powerful Supplement With Many Benefits, Fenugreek: An Herb with Impressive Health Benefits, Herbs, Vitamins, and Supplements for Testosterone, Kerry Boyle D.Ac., M.S., L.Ac., Dipl. eHealthMe is studying from 243 Elderberry users for its effectiveness, alternative drugs and more. One 2004 study of 60 people with influenza found that those who took 15 mL of elderberry syrup four times per day showed symptom improvement in 2 to 4 days, while the control group took 7 to 8 days to improve (10). CoQ10 is a powerful compound that helps your heart. Taking too much of this vitamin can cause neurological symptoms. 2021;21(1):112. doi:10.1186/s12906-021-03283-5, Macknin M, Wolski K, Negrey J, Mace S. Elderberry extract outpatient influenza treatment for emergency room patients ages 5 and above: a randomized, double-blind, placebo-controlled trial. People who labor or exercise in humid climates or have digestive issues can fall short on potassium; if you need to take both supplements, be sure to space them out by a few hours, he advises. Headaches. By using this site you agree to our Privacy Policy. Nausea and vomiting. Even essential nutrients can interfere with many common medications. It can also be harmful to unborn babies. If you are one of the 95 million Americans with high cholesterol, you might like the idea of taking a natural supplement to lower your levels. CoQ10 can also lower blood pressure. Herbal supplements and prescription medicines About one-half of adults in the United States say they have used one or more supplements in the past 30 days. If you opt to take multivitamins, the Mayo Clinic recommends choosing one that provides no more than 100 percent of the daily value of each nutrient. View abstract. J Altern Complement Med 1995;1:361-9. Other proposed uses of elderberry have not been supported by research. How to Determine if a Vitamin or Supplement Is Actually Right for You, Journal of the American Heart Association, Vitamin K: Why You Need It and Where to Find It, Confused About Multivitamins? Inflammatory cytokines, An evidence-based systematic review of elderberry and elderflower (, Chemical profiling and UHPLC-QToF analysis for the simultaneous determination of anthocyanins and flavonoids in Sambucus berries and authentication and detection of adulteration in elderberry dietary supplements using UHPLC-PDA-MS, 2021 US open forum: elderberry standards development, A 2020 study did not find black elderberry to improve symptoms or reduce the amount of time of illness. Dosage: How Much Elderberry Should I Take? The following are some of the findings from elderberry research: When evaluating the limited research available to date, it is important to keep in mind that: Elderberry may reduce the symptoms associated with the common cold or the flu if taken early, but there is no evidence to suggest that elderberry can prevent infection. They experienced nausea, vomiting, weakness, dizziness, numbness, and stupor (36). Elderberry is marketed mostly for immune support. Again, these necessary minerals will compete for absorption by the body, meaning you get less of each when you take them together, warns Dr. Cooperman. Health News and Information, Delivered to Your Inbox, Chronic obstructive pulmonary disease (COPD), Flu (influenza). All information is observation-only. However, the branches, bark, or leaves should not be used in cooking or juicing (2). United States Pharmacopeia (USP). Cyanogenic glycoside analysis in American elderberry, Advanced research on the antioxidant and health benefit of elderberry (, The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Therefore, determining the effects of currently available products may be difficult (17). Two supplements that have shown some benefit in your circumstance are fish oil and garlic. People who take a lot of zinc supplements may develop a copper deficiency. If you have eaten an unknown berry and develop concerning symptoms, get immediate medical attention. It is well documented that vitamin E supplementation can lead to increased bleeding in some people. Elderberry Gummies Elderberry gummies combine the best natural antioxidants in a single supplement. Int J Clin Pharmacol Res. Dont miss these signs youre not getting enough zinc. Thats the basic schedule. Therefore, elderberry cannot be recommended for any particular health benefit. 2017;31(4):533-554. doi:10.1002/ptr.5782, Wieland LS, Piechotta V, Feinberg T, et al. Antioxidants are natural components of foods, including some vitamins, phenolic acids, and flavonoids, that are able to help remove these reactive molecules. Among zincs many benefits, enhanced immunity ranks high. If you take a traditional blood thinner like warfarin, just the small amount of vitamin K in an MVM can cut its strength. Elderberry, meanwhile, contains tons of antioxidants called flavonoidsalong with vitamin A, B . See additional information. In a 2019 study on elderberry for cold and flu, elderberry appeared to reduce the duration of upper airway symptoms caused by the flu when taken at the onset of symptoms. Since the effects of grapefruit juice may last as long as 3 days, it should be avoided if you are taking atorvastatin (Lipitor), lovastatin (Mevacor, Altoprev) or simvastatin (Zocor). Schroder-Aasen T, Molden G, Nilsen OG. Read more: How to Determine if a Vitamin or Supplement Is Actually Right for You. Elderberry is not the same as American Elder, Elderflower, or Dwarf Elder, and these will not provide the same intended benefit as elderberry. While elderberry has shown promising results in the lab, research in humans and animals is still limited. View abstract. 25 people who take Elderberry and Multivitamin together, and have interactions are studied. However, the raw berries, bark, and leaves are poisonous. 2004;32(2):132-140. doi:10.1177/147323000403200205, Appenteng MK, Krueger R, Johnson MC, et al. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. However, another study in mice with high cholesterol found that a diet including black elderberry reduced the amount of cholesterol in the liver and aorta but not the blood (24). Additionally, the berries can be cooked and used to make juice, jams, chutneys, pies, and elderberry wine. Iron-deficiency anemia is the most common type of anemia and develops when you're not getting enough iron-rich foods, per the Mayo Clinic. Thank you, {{form.email}}, for signing up. Inflammation is one of the leading drivers of many common diseases. 2023 eHealthMe.com. 2010;10:17. This lessens the positive effects of consuming green tea. European elder. Taking a specific elderberry extract syrup (Sambucol, Nature's Way) seems to reduce. Toothaches. Some people like to make their own syrup from the dried berries, but these homemade . 2001 Apr-Jun;12(2):290-296. Look for supplements with a USP, NSF, or ConsumerLab label indicating they can be trusted to contain the listed ingredients. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Some researchers have suggested that the syrup shortens the duration of some illnesses and makes them less severe; however, the study findings have varied. Symptoms of eating uncooked berries, leaves, bark, or roots of the elderberry include nausea, vomiting, and diarrhea (2). But if you mix it with green tea, black tea, or curcumin supplements, your body wont absorb the mineral. 2021;26(5):1384. doi:10.3390/molecules26051384, Sidor A, Gramza-Michalowska A. Which vitamins are best paired and recommended to be taken together? Not only are they nutritious, but they may also help address cold and flu symptoms, support heart health, and fight inflammation and infections, among other benefits. Zakay-Rones Z, Thom E, Wollan T, Wadstein J. Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. Whether or not they are effective, they are usually safe to take. View abstract. What is elderberry used for? WebMD does not provide medical advice, diagnosis or treatment. Elderberry is most commonly used orally as a syrup. Here are 5 signs that an avocado has gone bad. Frequent urination. Other parts of the plant should be avoided as they contain a naturally occurring chemical compound called cyanogenic glycoside, which releases the poison hydrogen cyanide. Spacing out the two will help. These Vitamins & Supplements Might Interact With Your Birth Control, Studies have shown that a persons absorption of Vitamin K may be reduced when other fat-soluble vitamins such as Vitamin E and Vitamin D are taken together, says Dr. Chris Airey, M.D. 2016;8(2):59-66. While these results are promising, further large-scale human studies are. OTHER NAMES(S): Arbre de Judas, Baccae, Baises de Sureau, Black-Be, OTHER NAME(S): Arbre de Judas, Baccae, Baises de Sureau, Black-Be, Elderberry (Sambucus nigra) is the dark purple berry from the European elder tree. Picon PD, Picon RV, Costa AF, et al. generic drugs) are not considered. If you must take copper and also take zinc, space the two out by at least two hours, Dr. Cooperman says. Therapeutic Research Faculty 2018. As with several other fruits, eating a lot of elderberry fruit can cause: Elderberries should always be cooked and processed before theyre consumed. When you visit the site, Dotdash Meredith and its partners may store or retrieve information on your browser, mostly in the form of cookies. But only about 25% of people who take herbal supplements tell their health care providers. Vitamin C is found in strawberries, potatoes, and citrus. Its OK to drink green tea beveragessuch as matchajust dont do it with your iron supplements, Dr. Cooperman says; spread the two apart by a couple of hours. As a result, he says you want to wait at least two hours before taking Vitamin C with your Vitamin B12. 2023 UAB Health System. When we eat food, usually there is an array of vitamins, antioxidants, minerals, fats, and flora (the good germs that live in our digestive tract). Phytother Res. Commercial preparations of elderberry for the treatment of colds come in various forms, including liquids, capsules, lozenges, and gummies. We study millions of patients and 5,000 more each day. 2022;110. By Jennifer Lefton, MS, RD/N, CNSC, FAND There is one report of eight people falling ill after drinking the juice from freshly picked berries, including the leaves and branches, from the S. mexicana elder variety. You can safely take elderberry daily as long as you follow the recommended dosage instructions. Elderberry. Elderberry syrup, gummies, and juice are made from processed berries, which remove the poisonous compounds to make them safe to digest. If your doctor recommends a vitamin K supplement, avoid taking high dosages of vitamin E, which may counteract the effects of vitamin K, according to MedlinePlus. Nutrients. They're naturally flavored with. However, no large clinical studies have proven these benefits. Drug interactions are reported among people who take Elderberry and Vitamin c. Common interactions include impaired driving ability among females and anaemia among males. Dietary supplements vary widely when it comes to the nutrients they provide, as well as the dosage of those nutrients. In addition, the processing of elderberries, such as extraction, heating, or juicing, can reduce their antioxidant activity (4). Check out our favorite recovery essentials. Kidney stones or kidney damage. Some vitamins and supplements can interfere with blood-thinning blood pressure drugs, Dr. Glatter says. J Diet Suppl. Be sure youre aware of niacin flush and what you can do about this potential side effect. View abstract. Read our, Natural and Herbal Cold and Flu Treatments. It is most often taken as a supplement to treat cold and flu symptoms. This includes: There is no standard recommendation for dosing elderberry. Additionally, the processing of the berries and flowers can reduce their antioxidant activity. Furthermore, a study of 312 air travelers taking capsules containing 300 mg of elderberry extract three times per day found that those who got sick experienced a shorter duration of illness and less severe symptoms (11). While these results are promising, further large-scale human studies are needed. But when taking individual supplements, such as niacin or vitamin K, you may need to be cautious about potential interactions with other nutrients. Elderberry extract appears to be safe when taken in small doses. J Funct Foods. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Plus, they have many nutritional benefits. The berries are found in small black or blue-black bunches (1). Nick Blackmer is a librarian, fact-checker, and researcher with more than 20 years experience in consumer-oriented health and wellness content. Elderberry is safe to take all year round. Available at: https://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009). While both of these B vitamins are important, taking too much folic acid or folate can actually hide the symptoms of a vitamin B12 deficiency. Once standards are available, supplement companies can be held accountable for providing high-quality products. Too much vitamin A can lead to weaker bones and more bone fractures as you age. A 2004 study found symptom improvement four days sooner in those who were given 3 teaspoons of black elderberry four times daily. Cao G, Prior RL. Multivitamins typically include all of these 13 essential nutrients. But if you do take magnesium, Erin Stokes, ND, recommends not taking it at the same time as your multivitamin, as it may interfere with the absorption of smaller minerals found in the multivitamin, like iron and zinc. Clinical effectiveness of a combination of black elder berries, violet herb, and calendula flowers in chronic obstructive pulmonary disease: the results of a double-blinded placebo-controlled study. Another study in rats found that elderberry extract helped reduce inflammation and oxidative tissue damage (20, 21). On their own, both of these supplements offer a lot of benefits. It can cause bleeding episodes after a fall or injury, and theres a high risk of internal bleeding, he says. Cardiovascular disease risk biomarkers and liver and kidney function are not altered in postmenopausal women after ingesting an elderberry extract rich in anthocyanins for 12 weeks. 2020;35(11):3271-3277. doi:10.1007/s11606-020-06170-w, Hawkins J, Baker C, Cherry L, Dunne E. Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Elderberries should always be cooked and processed before theyre consumed. Since vitamin A is a fat-soluble vitamin, any excess is stored in the body. The stories you care about, delivered daily. Shutterstock (2) Potassium and calcium Omega-3 fish oil supplements may tame inflammation and improve your mood, but when you take these supplements with herbs that thin the bloodsuch as ginkgo biloba or garlicthey may prevent clotting and can lead to uncontrolled bleeding, Dr. Cooperman says. Despite these promising results, a direct reduction in heart attacks or other symptoms of heart disease has not yet been demonstrated, and further studies in humans are needed. Two herbal supplements, St. John's wort and Goldenseal, have such a high risk of interactions, that many experts recommend avoiding them entirely if you take any prescriptions.